Amoxi-Dry – Intramammary Dry Cow Ointment

For Prevention and Treatment of Mastitis During the Dry Period

Dosage Form:
Intramammary Ointment

Composition:
Each 4 g syringe contains:
200 mg Amoxicillin (as Amoxicillin Trihydrate)

Mechanism of Action:
Amoxicillin trihydrate is a broad-spectrum, bactericidal β-lactam antibiotic, highly effective against common mastitis-causing pathogens — primarily Gram-positive bacteria such as:

• Streptococcus agalactiae
• Staphylococcus aureus
• Beta-hemolytic Streptococci
• Escherichia coli

Amoxicillin inhibits bacterial cell wall synthesis, leading to bacterial lysis and death.

Indications:
Amoxi-Dry is indicated for the prevention of new intramammary infections and treatment of existing subclinical mastitis in dairy cows during the dry period.
It must be administered immediately after the last milking before the start of the dry period.
Its slow-release base ensures extended protection throughout the dry period against penicillin-resistant and Gram-positive bacteria.

Dosage & Administration:

1. Fully milk out the udder.
2. Wash the udder and teats thoroughly with warm water containing a mild disinfectant.
3. Dry with a clean towel.
4. Disinfect each teat end with alcohol.
5. Remove the syringe cap and insert the full contents into the teat canal.
6. Massage upward toward the milk cistern to distribute the ointment.

✅ Note: Use of partial insertion technique reduces the risk of introducing new infections during the dry period.

Withdrawal Periods:

• Meat: Do not slaughter animals for at least 30 days after last treatment.
• Milk: Not applicable during dry period treatment.

Precautions:

• Do not use in animals allergic to penicillin.
• Keep out of reach of children.

Storage:
Store in a dry place below 25°C (77°F).

Packaging:
Supplied in 4 g syringes.

Manufacturer:
Afarin Darou Pharmaceutical Company

Internal Teat Sealant for Dry Cow Therapy
Each 4 g syringe contains: Bismuth Subnitrate

Description:

Masti-Seal DC is a white, oily (paste-like) intramammary suspension free from antibiotics, designed to form a physical barrier within the teat canal, preventing the entry of mastitis-causing pathogens during the dry period.

✅ First teat sealant produced in Iran

Indications for Use:

Masti-Seal DC is used in dry cow therapy as a mechanical teat sealant, effectively blocking the teat canal throughout the entire dry period, thereby:

• • Preventing new intramammary infections
  • Reducing the incidence of clinical mastitis at calving

Directions for Use:

• 1. After the final milking and at the start of the dry period, disinfect the teat end using an alcohol swab.
  2. Insert the full contents of one Masti-Seal DC syringe into each teat.
  3. Do NOT massage the teat upward after administration.

Withdrawal Period:

• • When used alone, no milk or meat withdrawal period is required.

Storage Conditions:

• • Store between 15–30°C
  • Protect from freezing

Packaging:

Each box contains:

• • 20 syringes (4 g each)
  • Alcohol swabs

Contraindications & Restrictions:

• • No contraindications reported