Cefquinome-Based Intramammary Ointment

Cefquinome-Based Intramammary Ointment

Pharmaceutical Group: Antibiotic
Dosage Form: Intramammary Ointment

Composition:
Each 4-gram syringe contains:

• 150 mg Cefquinome (as sulfate)

Mechanism of Action:
Cefquinome is a broad-spectrum, fourth-generation cephalosporin antibiotic with strong bactericidal activity.
It acts by inhibiting the synthesis of peptidoglycan in the bacterial cell wall.
It is highly resistant to β-lactamase enzymes produced by Gram-negative bacteria, making it effective against coliformand staphylococcal mastitis in dairy cattle.

Indications:
Indicated for the prevention of subclinical mastitis and for protection against new intramammary bacterial infections caused by cefquinome-sensitive organisms, including:

• Streptococcus uberis
• Streptococcus dysgalactiae
• Streptococcus agalactiae
• Staphylococcus aureus
• Coagulase-negative Staphylococci

To be used during the dry period in dairy cows.

Dosage and Administration:
Use one 4 g single-use intramammary syringe (containing 150 mg cefquinome) per affected quarter immediately after the last milking.

1. Completely milk out the udder.
2. Clean and disinfect the teat thoroughly.
3. Ensure the syringe nozzle is sterile and uncontaminated.
4. Insert the nozzle either partially (~5 mm) or fully into the teat canal.
5. Inject the entire contents into the quarter.
6. Gently massage the teat and udder upward to aid distribution.

Note: Use each syringe only once.

Withdrawal Periods:

• Meat & offal: 2 days
• Milk:
  • If the dry period is ≤ 5 weeks: Do not use milk for 36 days after treatment.
  • If the dry period is > 5 weeks: Do not use milk for 1 day after calving.

Shelf Life: 24 months

Pcautions:

• Keep out of reach of children.

Storage Conditions:

• Store below 25°C
• Protect from heat and direct light

Packaging:
Box of 20 syringes, each containing 4 grams