Ceftiofur DC

Ceftiofur DC

(Intramammary Ointment)

Pharmacological Group:

Antibiotic

Dosage Form:

Intramammary Ointment

Composition:

Each 8 g syringe contains:

• Ceftiofur (Hydrochloride) – 500 mg

Mechanism of Action:

Ceftiofur is a third-generation cephalosporin antibiotic. Like other cephalosporins and penicillins, it exhibits a bactericidal mechanism of action. Cephalosporins bind to penicillin-binding proteins (PBPs) located in the cytoplasmic membrane of bacteria. This binding interferes with transpeptidase activity and other enzymes involved in cell wall synthesis, ultimately inhibiting bacterial cell wall formation. As a result, bacterial cell division and growth are disrupted, leading to cell lysis and death in susceptible organisms.

Indications:

Used for the treatment of infectious mastitis caused by Staphylococcus spp. and Streptococcus spp. during the dry cow period.

Dosage and Administration:

• Clean the teats thoroughly using warm water and an appropriate disinfectant.
• Ensure teats are completely dry.
• Strip milk completely from the quarters.
• Inject one 8 g syringe of ointment into each teat canal.
• After infusion, gently massage the teat to aid even distribution of the suspension.

Withdrawal Periods:

• Milk: Not applicable (to be used during the dry period only; a minimum of 30 days must elapse before the start of lactation)
• Meat: 16 days

Shelf Life:

24 months

Precautions:

• Keep out of reach of children.
• For veterinary use only.

Storage Conditions:

Store below 25°C and protect from sunlight.

Packaging:

Supplied in boxes containing 20 syringes of 8 g each.

Manufactured by:
Afarin Darou
For veterinary use only